abstract |
(57) [Summary] [Solution] The following general formula (1): [Wherein, Ar is a phenyl group which may have a substituent, Represents a naphthyl group, a pyridinyl group, a furyl group, a thienyl group, a quinolyl group or an indolyl group, and Y represents a group And Z represents a linear or branched alkylene group having 1 to 5 carbon atoms, and R 1 represents a hydroxyl group, an alkoxy group or —NH (CH 2 ) m COOH (where m is a number from 1 to 3) A hypoglycemic agent comprising an arylamide derivative represented by the formula or a salt thereof as an active ingredient. [Effect] The hypoglycemic agent of the present invention has an excellent hypoglycemic effect and can be used as a preventive / therapeutic agent for diabetes or obesity. It is very useful clinically because it can prevent the onset and prevent the progress of the disease. |