http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2002167383-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bb75b0b19820e3833ebdcb31603b242b |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D333-68 |
filingDate | 2001-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9f815a90fc621c153462d04e8f261e4a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4323fc15d36c065cffdb2faa09edcea1 |
publicationDate | 2002-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2002167383-A |
titleOfInvention | Method for producing 5-hydroxybenzo [b] thiophene-3-carboxylic acid derivative |
abstract | PROBLEM TO BE SOLVED: To provide a novel method for producing a benzothiophenic acid derivative (I) useful for producing a 5-hydroxybenzo [b] -thiophene-3-carboxylic acid derivative which is a specific PGD 2 antagonist I will provide a. SOLUTION: Hydroxy-protected 5-hydroxybenzo [b] thiophene (VII) is reacted with acetyl halide under the conditions of Friedel-Crafts reaction to oxidize the acetyl group of the obtained compound (VIII). Formula (I) characterized by deprotection: (Wherein R represents hydrogen or a hydroxy protecting group) or a reactive derivative thereof. |
priorityDate | 1998-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 183.