| abstract |
PROBLEM TO BE SOLVED: To provide an alcohol metabolism improving agent and a liver injury reducing agent which are composed of natural components and which are safe and excellent in a living body. SOLUTION: The alcohol metabolism improving agent and the liver damage reducing agent are a rice bran / soybean fermented extract obtained by inoculating a medium containing rice bran, soybeans and a carbon source with natto or Bacillus subtilis, and fermenting and culturing. It is characterized by containing. This rice bran Ingestion of the fermented soybean extract increased the rate of disappearance of blood ethanol and acetaldehyde, and showed significantly higher hepatic ADH and ALDH activities than in the Control group, thereby increasing alcohol metabolism. In addition, it suppresses an increase in serum GOT and GPT activities accompanying the administration of ethanol and carbon tetrachloride, Since it was recognized that the production of PO was also suppressed, liver damage due to alcohol and carbon tetrachloride can be reduced. |