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publicationDate 2002-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2002153702-A
titleOfInvention Chromatographic preparative method for tocotrienols
abstract PROBLEM TO BE SOLVED: To provide an operation method for fractionating tocotrienol from a raw material liquid containing a large amount of tocopherol and tocotrienol, which is not much different from a conventionally known simulated moving bed type chromatographic separation method. And a method that can be implemented on an industrial scale and saves on initial equipment costs and operating costs during operation. Kind Code: A1 A simulated moving bed type chromatographic separation in which a number of columns packed with a hydrophobic reverse phase liquid chromatography adsorbent having an affinity for tocotrienol relatively smaller than that for tocopherol is connected in an endless circulation system. To the apparatus, a raw material liquid of substantially 100% oil containing at least tens of percent of tocopherol and tocotrienol, and a desorbing liquid of ethanol-water = 90/10 are supplied to enrich the tocotrienol. The fractionated solution is separated from tocopherol and collected.
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