http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2002139485-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1010e3862914acdd087e73d76911ec6d |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-02 |
filingDate | 2000-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_69de5e0c442954ec1d7aa98cf4c17685 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8b45bbb0da97901fd875e4250f30bb30 |
publicationDate | 2002-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2002139485-A |
titleOfInvention | Screening method of preventive / therapeutic agent for diseases caused by α1ECa2 + channel dysfunction |
abstract | (57) Abstract: voltage-dependent alpha with 1E Ca 2+ channel reveals physiology, alpha 1E such as nociceptive pain, such as inflammatory pain depends on Ca 2+ channel Ca 2+ Provided is a method for screening a drug for preventing or treating a disease caused by channel dysfunction. SOLUTION: A test substance is administered to a voltage-dependent Ca 2+ channel α 1E subunit gene mutant mouse, and the degree of nociceptive pain in such a gene mutant mouse is compared and evaluated with a wild-type mouse. In addition, potential-dependent Ca A test substance can be brought into contact with cells / tissues derived from a 2+ channel α 1E subunit gene mutant mouse to measure and evaluate the degree of electrophysiological response in the spinal cord connected to the cells / tissues. |
priorityDate | 2000-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 635.