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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00
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filingDate 2000-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5e6d0112d17431aa9852e5ad88a1a59d
publicationDate 2002-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2002104992-A
titleOfInvention Composition for promoting colon epithelial cell renewal
abstract PROBLEM TO BE SOLVED: To provide a substance which promotes renewal of colon mucosal epithelial cells and a food composition containing an effective amount of the substance. SOLUTION: The growth rate of the epithelial cells when lactoferrin is acted on from the mucosal side by culturing a large intestinal mucosal piece using a culture device that reflects the phenomenon of the absorption process in the intestinal tract of a living body, and the rate of the new growth The apoptotic activity corresponding to was determined. As a result, there is a strong positive correlation between the rate of intestinal epithelial cell neogenesis and cell death by apoptosis, Lactoferrin accelerates both the growth and death of colonic epithelial cells, but without altering the equilibrium between them, while maintaining colonic mucosal function and morphology homeostasis, It has been found that colonic mucosal epithelial cells increase cell rotation.
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priorityDate 2000-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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