abstract |
[PROBLEMS] To provide an imidazole derivative compound useful for treating inflammatory cytokine-mediated diseases. SOLUTION: An imidazole derivative represented by the general formula (I). Specifically, 2- (4-cyanophenyl) -4- (4-fluorophenyl) -5- (4-pyridyl) -1H-imidazole, 4- (4-fluorophenyl) -2- (4- Methylsulfinylphenyl) -5- (4-quinolyl) -1H-imidazole and the like. |