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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-22
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filingDate 2000-09-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_556085cefa54c493b52d443043c8ba6f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aca403592276223c8385f00da09dbdbd
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publicationDate 2002-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2002088059-A
titleOfInvention Method for producing hydroxyproline
abstract (57) [Summary] Method for producing hydroxyproline [PROBLEMS] To provide a method for synthesizing hydroxyprolines using nitrone as a starting material, and a synthetic intermediate useful for the synthesis thereof. SOLUTION: The compound represented by the following general formula (3) is A method for producing hydroxyproline represented by the following general formula (10), wherein the hydroxyproline is deprotected if necessary, treated with an alcohol / mineral acid to obtain a corresponding carboxylic acid ester, and hydrolyzed with an alkali. [Formula 1] In the general formula (3), R 1 and R 2 are a protected hydroxyl group or a hydrogen atom, and at least one is a protected hydroxyl group.In the general formula (10), R 1 and R 2 are a hydroxyl group or a hydrogen atom. And at least one is a hydroxyl group.
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