| abstract |
(57) [Summary] The present invention provides a method, a pharmaceutical composition and a kit useful for treating cataract. The composition of the present invention comprises an estrogen agonist / antagonist and a pharmaceutically acceptable vehicle. Contains a carrier or diluent. The estrogen agonist / Antagonists are for example those of the formula (I): Wherein R 1 and R 2 may be the same or different and are each a methyl or ethyl group, or hydrogen or a benzyl group; or an optical or geometric isomer thereof; A pharmaceutically acceptable salt, N-oxide, ester, quaternary ammonium salt or prodrug thereof. While effective, the compositions and methods of treatment of the present invention substantially reduce the attendant burden of side effects associated with estrogen administration. |