| abstract |
(57) [Summary] [Problem] Cardiac disorders (eg, angina, arrhythmia, myocardial infarction, etc.), cardiovascular diseases such as hypertension, aldosteronemia, cerebral circulation disease, senile dementia, eye diseases (eg, glaucoma) And the like, and a non-peptide compound useful as a therapeutic or prophylactic agent for a renin-angiotensin system test and the like. SOLUTION: General formula (I) (Wherein, R 1 , R 2 , and R 4 each represent lower alkyl, hydroxymethyl, 1-hydroxyethyl or carboxyl, R 3 and R 5 each represent a hydrogen atom or a hydroxyl group, and X represents a carbon atom or a nitrogen atom. Wherein at least one hydroxyl group or carboxyl is present in the molecule) or a pharmaceutically acceptable salt thereof. |