abstract |
(57) [Summary]nContacting a cell with a compound that inhibits the binding of the leaderless protein to the transport molecule provides a method of inhibiting export of the leaderless protein from the cell. Leaderless proteins include FGF-1, FGF-2, IL-1α, IL-1β, CNTF, and HIV-tat. These methods are useful for treating various conditions, including tumors and diabetes. |