http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2001525378-A
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6929 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-543 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-76 |
filingDate | 1998-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2001-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2001525378-A |
titleOfInvention | Transfection particles |
abstract | (57) [Summary]nTransfection particles for delivery of nucleic acids to higher eukaryotic cells in vitro and in vivo comprise one or more nucleic acid molecules condensed by an organic cationic molecule. Isolated and stable particles are formed by complexing the same or different organic cationic precursor molecules with nucleic acid molecules other than by cross-linking with nucleic acid molecules, and by covalent bonding of the precursor molecules to each other on the nucleic acid template. can get. For specific cell targeting, these particles can carry targeting molecules, such as sugars. Preferred cationic precursor molecules are lipophilic surfactants that link to form lipids. These particles preferably contain only one nucleic acid molecule that makes the particles useful for gene therapy and for delivery of large DNA molecules. |
priorityDate | 1997-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 206.