| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1137 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D519-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-711
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-35
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-02 |
| filingDate |
1998-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
2001-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2001524318-A |
| titleOfInvention |
Inhibition of cell proliferation by lowering levels of PP5 |
| abstract |
(57) Abstract: The present invention provides a method for increasing the expression of p21 WAF1 / Cip1 in a cell to reduce the proliferation of the cell, comprising the step of reducing the level of PP5 protein in the cell. I do. The present invention further provides a method of treating or preventing an abnormal condition resulting from a defect in a tumor suppressor gene in a patient, which results in reduced induction of p21 WAF1 / Cip1 in the cell of the patient, the method comprising: Administering to the patient an amount of a compound effective to reduce the level of PP5 protein. |
| priorityDate |
1997-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |