| abstract |
(57) [Summary]nThe present invention relates to substituted 2-aminoacetamides represented by formula (II), or a pharmaceutically acceptable salt or prodrug thereof, wherein these substituents are defined herein. The present invention also relates to the treatment of neuronal damage following global and focal ischemia, the treatment or prevention of neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS), the treatment, prevention or amelioration of pain. The use of substituted 2-aminoacetamides, as anticonvulsants, as antidepressants, as local anesthetics, as antiarrhythmics, and for the treatment and prevention of diabetic neuropathy. |