| abstract |
(57) [Summary]nThe present invention relates to novel glycoprotein glycoform formulations comprising a substantially homogeneous glycoprotein glycoform or a combination thereof. More particularly, the invention relates to glycoprotein preparations, particularly including Fc glycoforms, and methods for producing, enriching, detecting and purifying such glycoforms. Furthermore, the invention relates to immunoglobulins, especially antibodies comprising a CH2 domain with specific N-linked glycans. Compositions, including pharmaceutical compositions, methods of using the preparations, and articles of manufacture containing the preparations are provided. |