| abstract |
(57) SUMMARY The present invention relates to potent somatostatin agonist compounds with high selectivity for receptor subtype 2. Disclosed are compounds of formula (I), including pharmaceutically acceptable salts and hydrates. The compounds are useful in treating diabetes, cancer, acromegaly, restenosis, depression, irritable bowel syndrome, pain and diabetic retinopathy. Many of these compounds are also active on oral administration. |