| abstract |
(57) SUMMARY The present invention describes the transdermal administration of certain indolone derivatives that are dopamine D 2 agonists. The method is a method of treating an individual suffering from Parkinson's disease, comprising administering an indolone derivative, such as ropinirole base or a pharmaceutically acceptable ropinirole salt, for a period of time effective to reduce the symptoms of the disease. Administration at a rate through the skin or mucosal tissue. Pharmaceutical formulations and drug delivery systems for administering the drug are also provided. |