http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2001516695-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-708 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7076 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-08 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7042 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7052 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7076 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-708 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-167 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-08 |
| filingDate | 1998-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2001-10-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2001516695-A |
| titleOfInvention | Use of purine nucleosides to regulate axonal outgrowth of central nervous system neurons |
| abstract | (57) [Summary]nMethods and compositions for modulating axonal outgrowth of central nervous system neurons are provided. Methods of stimulating axonal outgrowth of central nervous system neurons after injury (e.g., stroke, traumatic brain injury, cerebral aneurysm, spinal cord injury, etc.) and in epilepsy such as post-traumatic epilepsy and neuropathic pain syndrome Methods for inhibiting axonal outgrowth of central nervous system neurons are also provided. These methods generally involve contacting a central nervous system neuron with a purine nucleoside or analog thereof. Preferably, inosine or guanosine is used to stimulate axonal outgrowth, and 6-thioguanine is used to inhibit axonal outgrowth. These methods and compositions are particularly useful for regulating axonal outgrowth of mammalian central nervous system neurons, such as mammalian retinal ganglion cells. Pharmaceutical and packaged formulations containing the purine nucleosides or analogs thereof of the present invention are also provided. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2010150261-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2006517807-A |
| priorityDate | 1997-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 415.