http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2001514670-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16C10-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A90-10 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4742 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-306 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16C20-50 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G06F17-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G06F17-50 |
| filingDate | 1998-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2001-09-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2001514670-A |
| titleOfInvention | Bactericidal / permeability enhancing proteins: crystallization, X-ray diffraction, 3D structure determination, rational drug design, and molecular modeling of related proteins |
| abstract | SUMMARY OF THE INVENTION The present invention solves the three-dimensional structure of BPI, whereby the atomic coordinates of BPI from the analysis of sufficiently high resolution X-ray diffraction patterns for the determination of the three-dimensional structure of the protein, and Provided are methods for rational drug design based on the use of amino acid sequence data and / or X-ray diffraction data provided on a computer readable medium that is analyzed on a computer system having suitable computer algorithms. Atomic coordinates are then provided that generate structural information about related proteins, including the lipid binding and lipid transfer protein family including BPI, LBP, CETP, and PLTP. |
| priorityDate | 1997-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 277.