http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2001514511-A
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6811 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B30-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B50-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B40-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1048 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6816 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6813 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6816 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6813 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6811 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate | 1998-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2001-09-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2001514511-A |
titleOfInvention | Screening using fluorescence anisotropy to identify compounds with affinity for nucleic acids |
abstract | (57) [Summary]nThe present invention provides methods for screening for biologically active compounds, particularly those that bind to RNA sequences involved in the regulation of disease pathogenesis or physiology. This method assesses the stability and / or conformation of an RNA target in the presence and absence of a test ligand, and produces any measurable change in stability and / or conformation of the target RNA. Identifying the test ligand as a ligand. In a preferred embodiment, the effect of the ligand on target RNA stability and / or conformation is assessed by measuring the fluorescence deflection of the fluorescently labeled probe. |
priorityDate | 1997-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 28.