abstract |
(57) [Summary]nThe present invention provides the amino acid and nucleic acid sequences of the complete estrogen receptor β (ERβc) gene and the protein sequences related thereto. Based on the present disclosure, the present invention provides a method for identifying a substance that blocks or enhances ERβc-mediated transcriptional regulation, a method for determining whether ERβc or its isoform protein is expressed in a tissue or a cell, Provided are methods for identifying and using substances that block the transcriptional regulation of a gene by ERβc or its isoform protein, and further modulate other biological and physiological processes. |