| abstract |
(57) [Summary]nThe present invention relates to four novel Fc receptor-like proteins that are members of the Fc receptor family. In particular, isolated nucleic acid molecules are provided, which encode human FcR-I, FcR-II, FcR-III, and FcR-IV proteins. FcR-I, FcR-II, FcR-III, and FcR-IV polypeptides are also provided, as are vectors, host cells, and recombinant methods for producing them. The present invention further relates to screening methods for identifying agonist and antagonist FcR-I, FcR-II, FcR-III, and FcR-IV activities. Also provided are diagnostic methods for detecting a disease associated with the immune system, and therapeutic methods for treating a disease associated with the immune system. |