http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2001508429-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C323-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C323-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-235 |
| filingDate | 1997-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2001-06-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2001508429-A |
| titleOfInvention | Selective prostaglandin endoperoxide synthase-2 inhibitor |
| abstract | (57) [Summary] [Structural formula I] The present invention has the structural formula (I), wherein R is CH 3 , CH 2 CH 3 , (CH 2 ) 2 CH 3 , (CH 2 ) 3 CH 3 , (CH 2 ) 4 CH 3 , (CH 2 ) 5 CH 3 , (CH 2 ) 6 CH 3 , (CH 2 ) 2 O (CH 2 ) 3 CH 3 , CH 2 HC = CH (CH 2 ) 3 CH 3 , CH 2 C≡C (CH 2 ) 3 CH 3 , CCH 2 C≡C (CH 2 ) 2 CH 3 , CH 2 C≡C—CCH 2 CH 3 , CH 2 C≡C—CH 3 and CH 2 C≡CH, and R ′ is selected from the group consisting of: There is provided a compound selected from the group consisting of CH 3 , CF 3 , CH 2 Cl and CH 2 Br or pharmaceutically acceptable salts or hydrates thereof. Also provided is a method of inhibiting prostaglandin endoperoxide synthase-2 (PGHS-2) synthesis in a mammal. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2010504281-A |
| priorityDate | 1996-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 221.