http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2001506146-A

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filingDate 1997-12-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2001-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2001506146-A
titleOfInvention Biocompatible medical device with polyurethane surface
abstract (57) [Summary]nThe present invention provides a method for improving the biocompatibility of a device, particularly a medical device for invasive placement within a patient, as well as an improved medical device thereof. The present invention specifically reduces the thrombogenicity of polyurethane materials in contact with the blood of living patients. The method comprises providing a biocompatible medical device having a polymeric polyurethane component on a surface, exposing the polyurethane component of the medical device to a polar solvent suitable for the polymer component, the polar solvent being in a vapor phase. And maintaining exposure to said vapor phase for a time sufficient to reduce at least some of the irregular or sharp morphological features present on the surface of the polymer component. The present invention is a method for improving a medical device having at least one polymer part, the steps of providing a vapor phase containing a suitable solvent for the polymer part, and exposing the polymer part to said vapor phase. The method comprising: The method includes that the surface of the polyurethane component has morphological features (roughness, grooves, wave patterns, edge sharpness, deviation from planarity, etc.) and that the polyurethane component is exposed to the vapor phase. And increasing the planarity of the form. The method is accomplished without chemical reaction with the polymer component. The ability to control the amount of solvent that contacts the polymer component reduces the potential for damage to the polymer component. In particular, this vapor phase treatment minimizes the possibility of damage to the polyurethane structure, even if the polyurethane component is present as a thin wall (eg, less than 0.0762 mm), and reduces the size of protruding areas on the polyurethane outer surface. Can be reduced.
priorityDate 1996-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 30.