| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-0808
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C323-25 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-198
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-083
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C323-25
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 |
| filingDate |
1995-01-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
2001-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2001505180-A |
| titleOfInvention |
Geranylgeranyl-protein transferase inhibitors |
| abstract |
(57) [Summary]nThe disclosed compounds are homologs of CAAX-type proteins that can be modified by geranylgeranylation in vivo and selectively inhibit geranylgeranylation of several proteins. The relatively low activity of this compound on farnesyl protein transferase, which modifies several proteins important in cell replication, is regulated by the function of geranylgeranylated proteins, for example in certain cancers and inflammatory diseases The use of the compounds according to the invention for treating diseases is possible. The present invention further includes a chemotherapeutic composition containing the geranylgeranyl protein transferase type I inhibitor and a method for producing the same. |
| priorityDate |
1994-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |