| abstract |
(57) The present invention comprises pharmaceutically useful peptide derivatives of formula (I): PR 1 -R 2 -R 3 -R 4 , their pharmaceutically acceptable salts, and containing them For pharmaceutical compositions, wherein P, R 1 , R 2 , R 3 and R 4 have various meanings as defined herein. This novel peptide derivative is useful in treating MHC class II-dependent T-cell mediated autoimmune diseases or inflammatory diseases (eg, rheumatoid arthritis). The invention further relates to a process for the preparation of this novel peptide derivative and to the use of this compound in medical treatment. |