http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2001503130-A
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S436-815 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2430-40 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-567 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5308 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-567 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 |
filingDate | 1997-02-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2001-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2001503130-A |
titleOfInvention | Detection of dioxin-like compounds by detection of modified Ah receptor / ARNT complex |
abstract | (57) [Summary]nThe following group of compounds: polychlorinated dibenzodioxins, polychlorinated dibenzofurans, polychlorinated biphenyls, and structural analogs thereof, wherein the biological properties of polychlorinated dibenzodioxins, polychlorinated dibenzofurans, polychlorinated biphenyls A method for detecting a dioxin-like compound comprising as essential the structural analogs exhibiting characteristics of activity. The assay comprises: 1) an inactive Ah receptor in a form that can bind to a dioxin-like compound and can be transformed into an active form that forms a complex with ARNT and binds to a dioxin response element; and 2) Ah Use a sufficient amount of ARNT to optimize the deformation of the receptor. The test sample is contacted with the assay system under conditions effective to bind the dioxin-like compound to the Ah receptor and transform the Ah receptor into an active form that forms a complex with ARNT. The presence of a complex containing the modified Ah receptor and ARNT is detected. The presence of the complex comprising the modified Ah receptor and ARNT is detected using an antibody having a region capable of binding to ARNT when bound to the complex. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2005519640-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03075013-A1 |
priorityDate | 1996-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 404.