| abstract |
(57) [Summary]nThe present invention relates to cytotoxic myristylated peptides derived from the N-terminus of the Nef protein. The peptide preferably comprises a domain containing a net positive charge and an α-helical region. The present invention also relates to compounds that inhibit the cytotoxicity of Nef protein, methods for preventing Nef toxicity, HIV infection, and pharmaceutical compositions containing the compounds. |