| abstract |
(57) [Summary] General formula I Wherein the variables represent: R 1 is —CO—R 4 , —SO 2 —R 4 , —CONH—R 4 , COOR 4 , —C (＝ N) —R 4 , —C (＝ O) —NHR 4 and —C (＝ S) —NHR 4 ; R 2 is a branched or unbranched C 1 -C 6 -alkyl, which is itself a group of at most two Furthermore a phenyl optionally substituted by R 5, may have a pyridine or naphthyl ring (wherein, R 5 is a branched or unbranched C 1 -C 4 - alkyl, -O-C 1 ~C 4 - alkyl, OH, Cl, F, Br , I, CF 3, NO 2, NH 2, CN, COOH, COO-C 1 ~C 4 - alkyl, -NHCO-C 1 ~ C 4 - alkyl, -NHCOPh, -NHSO 2 -C 1 ~C 4 - alkyl, NHSO 2 -Ph, -SO 2 -C 1 ~C 4 - alkyl Contact It can represent -SO 2 Ph and; R 3 is piperidine -OR 6 and -NHR 6] - keto acid derivative and form of the tautomers and isomers, as well as physiologically acceptable thereof Of these compounds; and the use of these compounds as medicaments. |