| abstract |
(57) [Summary]nThe present invention provides compositions for use in raising an immune response against Porphyromonas gingivalis. The composition may comprise a suitable adjuvant and / or acceptable carrier and substantially purified P. Includes one P. gingivalis immunogen. This immunogen is composed of antigen 1, antigen 2, antigen 3, antigen 4 [where antigen 1 is P. Gingivalis antigen, which has an internal amino acid sequence: DLENKGEATLLVTFGSSYKAPRETYAKIEKTFAAAYPDQR; Gingivalis antigen having the internal amino acid sequence: DNPDENPLEGDITQTHTEKYVLAED; Gingivalis antigen, having the internal amino acid sequence: DVLLLDVTPLSLGIETMGGVMTYLTDANTTIPKLK; Gingivalis antigen having the internal amino acid sequence: VYNASISAVGNTSAIDPVVQIIHHN], and epitopes comprising fragments thereof. |