| Predicate |
Object |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1037
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-082
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-088
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B40-02 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C40B40-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-704
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-78
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-18 |
| filingDate |
1997-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
2001-02-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2001501600-A |
| titleOfInvention |
Tumor homing molecules, conjugates derived therefrom, and methods of using the same |
| abstract |
(57) Summary The present invention provides a tumor homing molecule that selectively homes to a tumor. The present invention also provides methods of using a tumor homing molecule to target an agent (eg, a drug) to a selected tumor or to identify a target molecule expressed by the tumor. The present invention is also, by contacting a molecule that specifically binds a tumor and alpha V-containing integrins, which provides a method of targeting a tumor comprising angiogenesis vasculature. The invention further provides molecules that can selectively home to the angiogenic vasculature. Further, the present invention provides target molecules that specifically bind to tumor homing molecules and are expressed by the angiogenic vasculature. The present invention also provides peptidomimetics that competitively inhibit the binding of antibodies and ligands that bind to the target molecule to the target molecule. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2007501014-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2016535058-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2015038064-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2016128505-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2008512391-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2012506419-A |
| priorityDate |
1996-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |