| abstract |
(57) [Summary]nThe present invention relates to an in situ gel-forming pharmaceutical composition for topical administration to a target organ of the body, wherein the pharmaceutical composition comprises one or more aggregate-forming surfactants, one or two Consisting essentially of an aqueous solution containing a gel-forming water-soluble polymer, a drug and optionally excipients, the drug is lipophilic, which binds more strongly to aggregates of surfactants than to water. An in-situ gel-forming pharmaceutical composition, whereby the release of the drug from the gel formed in situ to the target organ occurs slowly. |