| abstract |
PROBLEM TO BE SOLVED: To provide a nucleic acid sequence encoding ciliary neurotrophic factor (CNTF), a protein produced therefrom, and a pharmaceutical composition comprising CNTF. The present invention relates to the cloning, sequencing and expression of CNTF and provides, for the first time, a method for producing human CNTF using a nucleic acid sequence encoding human CNTF. In addition, CNTF or CNTs in various species and tissues using the CNTF nucleic acid sequences of the invention Nucleic acid sequences encoding F homologous molecules can be identified. A recombinant DNA molecule comprising a nucleic acid sequence encoding ciliary neurotrophic factor (CNTF), or a subsequence thereof comprising at least about 10 nucleotides. |