| abstract |
PROBLEM TO BE SOLVED: To provide a method for producing royal jelly tablets containing lactic acid bacteria. SOLUTION: A granulated mixture formed by mixing and stirring dry powder royal jelly, live bacterial powder of lactic acid bacteria, an excipient and a lubricant. The granulated mixture is dried by dehumidification at a low temperature until it can be made into a tablet, and the granulated mixture is tableted at a humidity of 40% or less and a temperature of 20 ° C. or less using a tableting machine. After forming a coating and applying an alcoholic solution of a mixture of alcohol-soluble protein and shellac extracted from cereals and applying a coating process to impart enteric properties, sugar coating is performed, and after sugar coating Then, the sugar coating film is subjected to a densification treatment under humidified conditions, and further, a glossing treatment is applied to the sugar coating layer. [Effect] It is not dissolved by gastric juice, has excellent enteric properties, maintains stable quality for a long time, and has an excellent effect on intestinal function. |