| abstract |
PROBLEM TO BE SOLVED: To solve the problem of physical stability and to improve the bioavailability of a preparation in the conjunctiva, cornea and lacrimal gland and the tolerance limit in the eye, in particular. The present invention provides a pharmaceutical preparation. SOLUTION: This is a water-based topical ophthalmic preparation containing cyclosporine, one of hyaluronic acid or salts thereof, and polysorbate 80, intended for topical ophthalmic use. Also, in the preparation of a formulation in the form of an aqueous solution, cyclosporin is used in connection with hyaluronic acid or one of its salts and polysorbate 80. |