http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2001299353-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3f12fd9e34ddc848815edfefc2f045ef |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-19 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-39 |
filingDate | 2000-04-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_748e4fa44bd8369365979649df84f5c3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3c6a9d1d5d869c018842b58af4aa1c6f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cc9e308372fd66ec3ea13dc5f46afeca http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d2777eba71c6531df2cacdf5f6d78b29 |
publicationDate | 2001-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2001299353-A |
titleOfInvention | Adjuvant consisting of rotavirus NSP4 |
abstract | PROBLEM TO BE SOLVED: To provide a production method capable of stably providing a practical and safe adjuvant for oral and nasal administration, and at the same time, providing a large amount and stably of a protein usable as the adjuvant. Aim. The present invention is based on the fact that rotavirus NSP4 has adjuvant activity, and provides an adjuvant comprising rotavirus NSP4. The rotavirus NSP4 protein used as the adjuvant is prepared by (1) a step of preparing a recombinant E. coli expression plasmid vector containing the rotavirus NSP4 protein or a gene encoding a part thereof and capable of producing the protein. And (2) a step of transforming host Escherichia coli with the recombinant Escherichia coli expression vector, (3) a step of culturing the transformed host Escherichia coli and producing a protein, and (4) a step of transforming the produced protein. It is manufactured by the process of separating and collecting. |
priorityDate | 2000-04-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 292.