| abstract |
[PROBLEMS] To provide a therapeutic or preventive agent for pulmonary failure, comprising a diaminotrifluoromethylpyridine derivative or a salt thereof as an active ingredient. SOLUTION: The therapeutic or preventive agent for lung failure contains a diaminotrifluoromethylpyridine derivative represented by the formula (I) or a salt thereof as an active ingredient. [Wherein, X represents -CW 1 R 1 group, -COCOR 2 group, -C W 1 NHCOR 2 groups, —C (＝ W 1 ) W 2 R 3 groups or — CW 1 N (R 4 ) R 5 groups, Y is an alkyl group, —CW 3 R 6 , -COCOR 7 , -NHCOR 7 , C-(= W 3) W 4 R 8 group, - (NH) m SO 2 R 9 group, - (N H) m SO 2 OR 10 group or - (NH) m SO 2 N (R 11 ) R 12 groups, R 1 , R 6 and R 9 are a chain or cyclic hydrocarbon group, a heterocyclic group, R 2 and R 7 are an alkyl group, an alkoxy group, etc., and R 3 , R 8 and R 10 are alkyl group, a phenyl group, R 4, R 5, R 11 and R 1 2 is an alkyl group, W 1 , W 2 , W 3 and W 4 are O or S, and m is 0 or 1] |