| abstract |
PROBLEM TO BE SOLVED: To provide a novel matrix metalloprotease production inhibitor which acts on a diseased part safely and effectively at a small dose and can treat cancer. SOLUTION: The following general formula (1): (Wherein, R 1 , R 2 , R 3 and R 4 represent the same or different hydrogen atoms or lower alkyl groups, R 5 represents a hydrogen atom, a lower alkyl group or a lower acyl group, and X Represents a monosaccharide residue or an oligosaccharide residue in which a hydrogen atom of a hydroxyl group in the sugar residue may be substituted with a lower alkyl group or a lower acyl group; n is an integer of 0 to 6; Is an integer of 1 to 6), which is a matrix metalloprotease production inhibitor containing a chromanol glycoside represented by the following formula: |