| abstract |
(57) [Summary] (Modified) [Problem] Suitable for cross-flow and other test methods for detecting the presence of an analyte in a test sample, stable even when humidity fluctuates, and even after long-term storage A conjugate that forms a stable covalent bond with a molecule containing a free primary or secondary amine or sulfhydryl group. A conjugate having the structural formula (1) or (2), X is a solid phase substance having a hydroxyl group; R 5 is (CH 2 ) n (N H (CH 2 ) m ) p , n is 2 to 8, m is 2 to 8, p is 0 to 3, R 6 and R 7 are alkyl groups, Any selected from the group consisting of cyclic alkyl groups, aromatic groups or heterocyclic groups, containing from 0 to 8 hydroxyl, hydroxycarbonyl or aminocarbonyl groups, and wherein Q contains a free primary or secondary amine group A conjugate wherein L is any molecule comprising a sulfhydryl group. |