| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8f4c2477bdea308bc9dec3feded37457 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-19
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-15
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 |
| filingDate |
2000-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d02e2c87273ea3a1d06773a8e5acdc67
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b6684bede91de6bf0017727db41b7fca
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0d917a1da09683a9e66e99b7e82350a5 |
| publicationDate |
2001-09-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2001245663-A |
| titleOfInvention |
Promoter that regulates expression of Aggrecanase-1 (ADAMTS4) |
| abstract |
(57) [Summary] [Problem] The object of the present invention is to clone a promoter region that regulates the transcription of aggrecanase-1 gene associated with various diseases, to elucidate the nucleotide sequence, and The purpose of the present invention is to construct a system for screening compounds that affect the expression of -1. SOLUTION: The base sequence of the promoter region upstream of the aggrecanase-1 gene is clarified, and a vector in which a reporter gene is connected downstream of the promoter region of the aggrecanase-1 gene and a promoter region in which a part thereof is deleted is provided. Once produced and introduced into mammalian cells, it has become possible to screen for compounds that affect aggrecanase-1 expression. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2009537123-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005045025-A3 |
| priorityDate |
2000-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |