http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2001226322-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_afea2aa6f1f892c1456cf7d7a8bc0242 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-52 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-757 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C51-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-343 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C59-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J31-24 |
| filingDate | 2000-02-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9ff81c1c08de6a3b3b2579ac7cd7583c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6fcdf866f2e910c0a8ff388b2a1aacba |
| publicationDate | 2001-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2001226322-A |
| titleOfInvention | Method for producing 2-substituted propionic acid |
| abstract | PROBLEM TO BE SOLVED: To provide an efficient method for producing a 2-substituted propionic acid, which converts halomethylstyrene into a styrene derivative and reduces self-polymerization in carbonylation. SOLUTION: 1) An adipic acid diester is reacted with an alkoxide M (OR) n (R is an alkyl group of C5 or less, M is an alkali metal or an alkaline earth metal), followed by coupling with halomethylstyrene. 2) reacting the resulting intermediate with carbon monoxide and water or an alcohol in the presence of a metal catalyst to give a compound of general formula II, Further, 3) 2- of the general formula III for decarboxylation / hydrolysis Method for producing substituted propionic acid (loxoprofen). (R ′ is an alkyl group of C4 or less, R ″ is hydrogen or C Represents an alkyl group of 4 or less, and R 'and R "may be the same or different.) (R and M are the same as above, n represents the valence of M, and n (OR) s may be the same or different.) |
| priorityDate | 2000-02-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 165.