| abstract |
[PROBLEMS] To provide compositions and methods for treating and diagnosing diseases associated with protein kinase C (particularly C-ε). An oligonucleotide capable of specifically hybridizing to a PKC gene or mRNA and a specific PKC An oligonucleotide capable of specifically hybridizing to an isoenzyme, a set of isoenzymes, or mRNA. A method for treating a condition susceptible to therapeutic intervention by modulating the expression of protein kinase C using an oligonucleotide capable of specifically hybridizing to a PKC gene or mRNA. Compositions and methods for the treatment, detection and diagnosis of diseases associated with protein kinase Cα and its specific transcripts. Novel nucleic acid sequence encoding the 3 'untranslated region of human protein kinase Cα. Polynucleotide probe for PKCα. |