| abstract |
(57) [Problem] To provide an inhibitor of α-MSH, and to provide a skin external preparation for improving a disease associated with α-MSH or a reaction unfavorable to a living body, for example, a pigment abnormality such as dullness. SOLUTION: An α-MSH inhibitor comprising a compound represented by the general formula (I) and / or a physiologically acceptable salt thereof is contained in an external preparation for skin such as cosmetics. Embedded image Formula (I) (wherein, R1, R2, R3, and R4 each independently represent an alkyl group having 1 to 4 carbon atoms, and R5 represents an alkyloxy group, an acyloxy group, or a hydroxyl group) |