abstract |
(57) [Summary]nPROBLEM TO BE SOLVED: To provide a 4'-trifluoromethyl-2-methylbiph. Enyl and 4'-trifluoromethyl-biphenyl- For producing 2-carboxylic acid from o-tolyl metallate Provision of law.nSOLUTION: The formula (I)nEmbedded imagen (Wherein R is methyl or carboxyl) A process for the preparation of a product, comprising an ortho-tolyl metallate of the formula (II) With a compound of formula (III)nEmbedded imagen (Where M is -MgF, -MgCl, -MgBr, -M gI, -Li, -ZnF, -ZnCl, -ZnBr or Is -ZnI, and X is F, Cl, Br, I, N 2 + , Linear or branched (C 1 ~ C 20 ) -Alkoxy, ant Sulfonic acid or alkyl sulfonate) And coupling in the presence of Ni, Pd or platinum metal catalyst In the formula (I), R is CH 3 Form a compound that is And optionally, where R of formula (I) is CH 3 Which is Oxidizing the compound to form a compound of formula (I) wherein R is carboxyl. A method comprising obtaining a compound. |