abstract |
(57) [Problem] To genetically transform somatic cells in the skin of a living animal. SOLUTION: An agent for genetically transforming somatic cells in the skin of a living animal. The drug comprises an inert, high-density carrier particle, which is coated with a copy of the foreign gene structure, is small in size relative to the size of the cell, and , A DNA sequence encoding the protein and a proximity regulatory sequence effective to express the protein in the cell. |