http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2001199974-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_42e94091a4fc81b8d0237117707cc7ee |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D305-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-337 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-335 |
| filingDate | 2000-12-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_18df591212f639f4cb0db566c78819ae http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_926e7488e4fbca8621d73d14529b7cc5 |
| publicationDate | 2001-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2001199974-A |
| titleOfInvention | 7,8-Cyclopropataxanes |
| abstract | PROBLEM TO BE SOLVED: To provide a structurally novel taxol derivative having antitumor activity. The compound of the following formula I: (Wherein R 1 is -COR z (where R z is t-butyloxy, C 1-6 alkyl, C 2-6 alkenyl, C 2-6 alkynyl, C 3-6 cycloalkyl, or 1 to 3 The same or different C 1-6 alkyl, C 1-6 alkoxy, halogen or phenyl optionally substituted with —CF 3 group), and R 2 is C 1-6 alkyl, C 2-6 Alkenyl, C 2-6 alkynyl, C 3-6 cycloalkyl, or a formula —W—R x wherein W is a bond, C 2-6 alkenediyl, or — (CH 2 ) t — (where t is 1-6), R x is naphthyl, furyl, thienyl or phenyl, and R x is 1-3 identical or different C 1-6 alkyl, C 1-6 alkoxy, halogen or- a group of CF 3 may be substituted with group], R 3 is -OCOR, -OCOOR, H or It is OH, and R 4 is hydrogen, wherein R is C 1-6 alkyl). The compound of formula I of the present invention has antitumor activity. |
| priorityDate | 1992-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 135.