| abstract |
(57) [Summary] [PROBLEMS] By imparting a sliding function to a functional molecule such as a ribozyme, it is possible to efficiently search for and act on a target even if it is a part buried inside a complicated entangled nucleic acid structure. A highly functional chimeric molecule is provided. SOLUTION: A chimeric molecule comprising a molecule capable of sliding, or a region having a binding affinity for the molecule or a molecule forming a complex with the molecule, and a functional region, and encodes the chimeric molecule An expression vector containing DNA, and a pharmaceutical composition containing the chimeric molecule or the expression vector as an active ingredient. |