| abstract |
(57) [Summary] (Modified) [Solution] General formula 1 [A 1 and A 2 are the same or different and may have a substituent; a C4-7 divalent hydrocarbon group; A 3 may have a substituent; a C1-4 divalent hydrocarbon group; A 4 is hydrogen or the like; a 1 and a 2 are the same or different and are a single bond or the like; Q 1 and Q 2 are the same or different, and may have a substituent such as a cyclic hydrocarbon group; Q 3 is a heterocyclic group or the like which may have a substituent; X 1 is a carboxyl group which may be esterified Is shown. And a salt thereof. [Effect] The present succinamic acid derivative or a salt thereof exhibits a potent squalene synthase inhibitory activity and is useful as a medicament for preventing and / or treating hypercholesterolemia, hyperlipidemia, and arteriosclerosis. |