| abstract |
(57) [Summary] (Problem corrected) [Problem] Neuropeptide Y antagonism, ie, obesity, Provide a compound having a therapeutic effect on diabetes, hypertension and the like. SOLUTION: General formula (1): [Wherein, R 1 is a monocyclic or polycyclic carbocyclic or heterocyclic group which may have a substituent, and R 2 is a bond or a lower alkylene such as hydroxy, oxo, etc. , R 3 is piperidinediyl or a formula: Wherein R 7 is indolylmethyl and n is 1 to 4, and R 4 is an optionally substituted aryl, aralkyl or heterocyclic ring. R 5 is a bond, lower alkylene or a formula: (Wherein m is 0 or 1), R 6 is hydrogen or a hydroxy group, Is an optionally substituted divalent nitrogen-containing saturated heterocyclic group]] or a salt thereof. |