| abstract |
(57) [Summary] [Problem] A gelatinase activity inhibitor having excellent antagonism to the activity of gelatinase, which has a great effect on skin aging, and capable of preventing, preventing and improving skin aging, for anti-aging A skin external preparation is provided. SOLUTION: Togeban reishi (Annona muricata) L.), Calophyllum br. asiliense Cambess.), Quassia amar a L.), Fleurya aestua ns (L.) Gaud.), Milkia Sfaerocarpa (Myrci) a sphaerocarpa DC.) and one or more plants selected from Hyptis crenata Pohl ex Benth., or a gelatinase activity inhibitor containing a solvent extract thereof, and for anti-aging External preparation for skin. |